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Ion Channels and Transporters of Epithelia in Health and Disease de Kirk L. Hamilton

Ion Channels and Transporters of Epithelia in Health and Disease: Physiology in Health and Disease

Editat de Kirk L. Hamilton, Daniel C Devor
en Limba Engleză Hardback – 15 dec 2015
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.
 
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Specificații

ISBN-13: 9781493933648
ISBN-10: 1493933647
Pagini: 1019
Ilustrații: XIV, 1019 p. 181 illus., 44 illus. in color.
Dimensiuni: 155 x 235 x 54 mm
Greutate: 1.61 kg
Ediția:1st ed. 2016
Editura: Springer
Colecția Springer
Seria Physiology in Health and Disease

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Part I: Basic Epithelial Ion Transport Principles and Function.- Part II: Epithelial Ion Channels and Transporters.- Part 3: Pharmacology of Potassium Channels.- Part IV: Diseases in Epithelia. 

Textul de pe ultima copertă

This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. 
The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.


Caracteristici

Updates readers on essential findings concerning the cell physiology, biochemistry, pathophysiology and pharmacology of epithelial ion transport Addresses both basic research and clinical aspects All chapters written by leading scientists and clinicians Includes supplementary material: sn.pub/extras