Acquisition and dissemination of knowledge have been an integral part of human life. This is an era of knowledge which is acquired through education. Learning takes place under certain conditions which can be created by competent and imaginative teachers. One step in developing high quality and commitment-driven faculty is, understanding the factors associated with teaching quality. One of these factors is Job Satisfaction.Research relating to Job Satisfaction of teachers is of primary importance because faculties are the main asset of an educational institution system.This research focuses on job characteristics model in predicting job satisfaction levels by measuring job dimensions, critical psychological state, work outcome measures and individual growth-need strength of college teachers in Madurai District. The study also attempts to evaluate the causes and consequences of work-family balance and its impact.This research will enable the management, educational institutions and policy makers to predict in advance the relevant facets of job satisfaction, dissatisfaction, stress and the causes of stress.