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Kratom: History, Science and Therapeutic Potential

Editat de Jack E. Henningfield, Chad E. Beyer, Robert B. Raffa
en Limba Engleză Paperback – sep 2025
Kratom: History, Science and Therapeutic Potential is the first book to address the unregulated, widespread availability of kratom, with its weak opioid and stimulant effects, coupled with limited awareness of it by healthcare professionals. Kratom has great therapeutic utility and medicinal potential, but more study, caution, and possible regulation is needed. It discusses geographical sourcing, historical uses, current worldwide uses, and potential for treatment of other medical conditions. Most exciting for healthcare professionals will be the implications of this substance's potential for treatment of diseases like depression, ADHD, PTSD, and substance-use disorder, particularly opioid use disorder (OUD).

Moreover, kratom and its active alkaloid mitragynine are getting remarkable attention at federal and local governments as more than eight million Americans consume this product annually. Yet, the paucity of information for researchers and clinicians is troublesome.

  • Provides healthcare scientists and researchers with awareness on kratom and its emerging trend as a therapy for medical use for many medical applications
  • Presents cutting-edge science for healthcare providers of a substance that will soon be as topical as medical marijuana
  • Offers scientists and others information to help those involved in emerging decisions regarding legal status and regulations
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Specificații

ISBN-13: 9780443274121
ISBN-10: 0443274126
Pagini: 250
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE

Cuprins

1. Plant sources (species and geography) and components of Kratom
2. Historical uses
3. Recent patterns and reasons for use
4. Current legal and regulatory status
5. Chemistry (structures, properties, computer modeling)
6. Pharmacology (receptor binding, 2nd-messenger transduction, biased ligand)
7. Active metabolite (7-OHM)
8. Isolated tissue and in vivo studies (analgesia, constipation, etc.)
9. Pharmacokinetics (ADME)
10. Current use for self-management of SUD; withdrawal
11. Pain and other CNS disorders
12. Natural supplements and direct-to-consumer Kratom sales
13. IP on naturally occurring alkaloids
14. Drug-drug interactions
15. Susceptible populations
16. Purity and other quality control issues
17. Kratom entrepreneurship
18. Equity investment into the space
19. Medical marijuana as template for kratom