For centuries the Cleansers have risked their lives for the Catholic Church. Their mission is to rid the world of the unnatural filth that stalks the night seeking human prey. Tony White has dedicated his life to stand between humanity and the things that go bump in the night - and what a life it's been. Unbeknownst to his Vatican masters, Tony hides the secret of his own immortality, a secret that he's carried for 164 years. Facing the greatest battle of his long career, Tony finds himself chasing a pack of bloodthirsty vampires, a hungry werewolf, and a Hell-spawned demon, all of which are bent on terrorizing the same woman, a beautiful young redhead named Erin. As the hunt crisscrosses the hot and humid Atlanta nights, Tony begins to suspect that there may be more to this case than he originally believed. Someone wants him dead, permanently, and all the evidence points towards a conspiracy that goes deeper than he ever could have imagined. With the help of the only two humans in Atlanta who know his secret, Tony must find the truth behind the seductive Erin and a mysterious mansion in the north Georgia mountains called "La Miseria di Bianco."