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Leukodystrophies: International Review of Child Neurology

Autor S Naidu
en Limba Engleză Hardback – 10 mar 2011
The leukodystrophies are serious, progressive disorders of demyelination, manifesting themselves in infancy or early childhood and progressing rapidly, leading to loss of sight, hearing, speech, and ambulation, and early death. A comprehensive guide to the genetics and pathogenesis of these disorders, as well as their clinical features, diagnosis and therapy, is needed, particularly as their early identification can allow more effective treatment.
This book is the only up-to-date, comprehensive text on leukodystrophies. Its purpose is to summarize for the reader all aspects of the inherited disorders of myelin in children and adults. After a comprehensive overview of myelin and the role of oligodendrocytes, astrocytes and microglia in white matter disease, chapters are then devoted to individual disorders, covering their biochemical and molecular basis, genetics, pathophysiology, clinical features, diagnosis, treatment and screening. The final chapters address therapeutic approaches in leukodystrophies and present a clinical approach to diagnosing leukoencephalopathies in children and adults.
The book was conceived by Hugo Moser, whose research led to major developments in the treatment of adrenoleukodystrophy, and is dedicated to him by his colleagues.
Readership: Paediatric and adult neurologists, paediatricians, geneticists.
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Specificații

ISBN-13: 9781907655098
ISBN-10: 1907655093
Pagini: 252
Dimensiuni: 174 x 245 x 19 mm
Greutate: 0.7 kg
Editura: Mac Keith Press
Seria International Review of Child Neurology

Locul publicării:Chichester, United Kingdom

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