The present book, considering the key question about the origin of life and mind, suggests an innovative thesis of philosophy of biological science, which is an uncharted area so far. System Philosophy logically shows that things exist by the union of opposites. Treating genetic code (information) as nonphysical is the vital step to reach the new philosophy about biology. Importantly, life is a system formed by the opposite entities called macromolecule (mainly DNA) and information. This leads to the new system model of life and evolution, which synthesizes the opposite views of science and religion. The materialist theory of evolution advanced by Charles Darwin is radically modified in this book. Also it would equip us to tackle the problem of missing links in an ingenious way. The age-old problems of mind-body dualism and self-consciousness are solved here through the system model of mind. Also the analysis is extended to develop the system philosophy of religion, which effectively provides a new thesis about God. The present book is written in a pedagogic style, by explaining all concepts in a basic manner, making use of suitable Tables and Diagrams. So the book would serve as text as well as reference for all inquisitive readers.