Living without an Amygdala
Editat de David G. Amaral, Ralph Adolphsen Limba Engleză Hardback – 20 iul 2016
Bringing together leading researchers, this book comprehensively covers what is known about the amygdala, with a unique focus on what happens when this key brain region is damaged or missing. Offering a truly comparative approach, the volume presents research on rats, monkeys, and humans. It reports on compelling cases of people living without an amygdala, whether due to genetic conditions, disease, or other causes. The consequences for an individual's ability to detect danger and regulate emotions--and for broader cognitive and social functions--are explored, as are lessons learned about brain pathways and plasticity. The volume delves into the role of the amygdala in psychiatric disorders and identifies important directions for future research. Illustrations include six color plates.
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Specificații
ISBN-13: 9781462525942
ISBN-10: 1462525946
Pagini: 430
Dimensiuni: 152 x 229 x 25 mm
Greutate: 0.74 kg
Ediția:1
Editura: Guilford Publications
Colecția Guilford Press
ISBN-10: 1462525946
Pagini: 430
Dimensiuni: 152 x 229 x 25 mm
Greutate: 0.74 kg
Ediția:1
Editura: Guilford Publications
Colecția Guilford Press
Public țintă
Professional and Professional Practice & DevelopmentNotă biografică
David G. Amaral, PhD, is Distinguished Professor of Psychiatry and Neuroscience and Research Director of the UC Davis MIND Institute at the University of California, Davis. His interests include the neurobiology of social behavior and the development, neuroanatomical organization, and plasticity of the primate and human amygdala and hippocampal formation, with a particular focus on understanding the biological bases of autism spectrum disorder. Dr. Amaral is Director of Autism BrainNet, which solicits postmortem brain tissue to facilitate autism research, and Editor-in-Chief of Autism Research. He is a past president of the International Society for Autism Research and a Fellow of the American Association for the Advancement of Science, among other honors.
Ralph Adolphs, PhD, is Bren Professor of Psychology and Neuroscience at the California Institute of Technology. He leads a social neuroscience laboratory that investigates the psychological and neurobiological underpinnings of social behavior, with a particular focus on the role of the human amygdala and prefrontal cortex. A major goal is to make comparisons and contrasts across different clinical populations and research techniques. Dr. Adolphs is a past president of the Association for the Scientific Study of Consciousness, a Fellow of the Association for Psychological Science, and a recipient of the Distinguished Investigator Award from the Social and Affective Neuroscience Society, among other honors.
Ralph Adolphs, PhD, is Bren Professor of Psychology and Neuroscience at the California Institute of Technology. He leads a social neuroscience laboratory that investigates the psychological and neurobiological underpinnings of social behavior, with a particular focus on the role of the human amygdala and prefrontal cortex. A major goal is to make comparisons and contrasts across different clinical populations and research techniques. Dr. Adolphs is a past president of the Association for the Scientific Study of Consciousness, a Fellow of the Association for Psychological Science, and a recipient of the Distinguished Investigator Award from the Social and Affective Neuroscience Society, among other honors.
Cuprins
1. A Tale of Survival from the World of Patient S. M., Justin S. Feinstein, Ralph Adolphs, & Daniel Tranel
2. A Synopsis of Primate Amygdala Neuroanatomy, Cynthia M. Schumann, Martha V. Vargas, & Aaron Lee
3. A Short History of the Lesion Technique for Probing Amygdala Function, David G. Amaral
4. Role of the Rodent Amygdala in Early Development, Emma Sarro & Regina M. Sullivan
5. Foraging in the Face of Fear: Novel Strategies for Evaluating Amygdala Functions in Rats, Jeansok J. Kim, June-Seek Choi, & Hongjoo J. Lee
6. Lifetime Consequences of Early Amygdala Damage in Rhesus Monkeys, Eliza Bliss-Moreau, Gilda Moadab, & David G. Amaral
7. The Effects of Neonatal Amygdala Lesions in Rhesus Monkeys Living in a Species-Typical Social Environment, Jocelyne Bachevalier, Mar Sanchez, Jessica Raper, Shannon B. Z. Stephens, & Kim Wallen
8. The Central Nucleus of the Amygdala Is a Critical Substrate for Individual Differences in Anxiety, Jonathan A. Oler, Andrew S. Fox, Alexander J. Shackman, & Ned H. Kalin
9. Monkeys without an Amygdala, Elisabeth A. Murray & Sarah E. V. Rhodes
10. Consequences of Developmental Bilateral Amygdala Lesions in Humans, Ralph Adolphs
11. Behavioral Consequences and Compensatory Adaptations after Early Bilateral Amygdala Damage in Monozygotic Twins, Alexandra Patin & René Hurlemann
12. Consequences of Selective Bilateral Lesions to the Basolateral Amygdala in Humans, Jack van Honk, David Terburg, Helena Thornton, Dan J. Stein, & Barak Morgan
13. Attending to the World without an Amygdala, Rebecca M. Todd, Adam K. Anderson, & Elizabeth A. Phelps
14. Implications for Understanding Amygdala Function in Mental Disorders, Christopher S. Monk & Daniel S. Pine
Epilogue, David G. Amaral & Ralph Adolphs
Index
2. A Synopsis of Primate Amygdala Neuroanatomy, Cynthia M. Schumann, Martha V. Vargas, & Aaron Lee
3. A Short History of the Lesion Technique for Probing Amygdala Function, David G. Amaral
4. Role of the Rodent Amygdala in Early Development, Emma Sarro & Regina M. Sullivan
5. Foraging in the Face of Fear: Novel Strategies for Evaluating Amygdala Functions in Rats, Jeansok J. Kim, June-Seek Choi, & Hongjoo J. Lee
6. Lifetime Consequences of Early Amygdala Damage in Rhesus Monkeys, Eliza Bliss-Moreau, Gilda Moadab, & David G. Amaral
7. The Effects of Neonatal Amygdala Lesions in Rhesus Monkeys Living in a Species-Typical Social Environment, Jocelyne Bachevalier, Mar Sanchez, Jessica Raper, Shannon B. Z. Stephens, & Kim Wallen
8. The Central Nucleus of the Amygdala Is a Critical Substrate for Individual Differences in Anxiety, Jonathan A. Oler, Andrew S. Fox, Alexander J. Shackman, & Ned H. Kalin
9. Monkeys without an Amygdala, Elisabeth A. Murray & Sarah E. V. Rhodes
10. Consequences of Developmental Bilateral Amygdala Lesions in Humans, Ralph Adolphs
11. Behavioral Consequences and Compensatory Adaptations after Early Bilateral Amygdala Damage in Monozygotic Twins, Alexandra Patin & René Hurlemann
12. Consequences of Selective Bilateral Lesions to the Basolateral Amygdala in Humans, Jack van Honk, David Terburg, Helena Thornton, Dan J. Stein, & Barak Morgan
13. Attending to the World without an Amygdala, Rebecca M. Todd, Adam K. Anderson, & Elizabeth A. Phelps
14. Implications for Understanding Amygdala Function in Mental Disorders, Christopher S. Monk & Daniel S. Pine
Epilogue, David G. Amaral & Ralph Adolphs
Index
Recenzii
"An excellent book from two of the major students of the amygdala. This volume reviews, outlines, and organizes knowledge about the amygdala--the orchestrator of emotion--in a wonderfully clear and systematic fashion that brings our understanding from its solid foundation in rodents to a new level. This is a 'must read' for anyone interested in emotion and its psychological and biological consequences."--Eric Kandel, MD, Director, Kavli Institute for Brain Science; Co-Director, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University
"Over the past several decades much has been learned about the role of the amygdala in behavior, mostly from studies of nonhuman animals. This volume makes a useful contribution by bringing together the current state of knowledge about the human amygdala."--Joseph E. LeDoux, PhD, Center for Neural Science and Department of Psychology, New York University
"Living without an Amygdala provides an important corrective to the popular belief that the primary function of the amygdala is to create a state of fear. The elegant research in this volume affirms the adage that ugly facts often destroy beautiful ideas, and provides neuroscientists and psychologists with a richer understanding of the amygdala."--Jerome Kagan, PhD, Department of Psychology (Emeritus), Harvard University
"This book offers a novel window into the function of the amygdala across development by interweaving controlled primate studies of amygdala lesions with detailed histories of humans who have bilateral amygdala damage. The marriage of experimental neuroscience with personal and empathic narratives results in an informative, compelling work. This book will surely become a classic for students, instructors, and researchers who study the amygdala, human fear and anxiety, and the etiology of mental disorders. It should be of much interest in courses on affective and cognitive neuroscience, as well as abnormal psychology, psychiatry, and developmental psychopathology."--Katie McLaughlin, PhD, Department of Psychology, University of Washington
-A comprehensive and compelling overview of this small, but incredibly complex, brain region….Stylistically, the book shifts back and forth between prose-like storytelling and scientific journal articles. This style conveys and elucidates the existing literature, while also illustrating the real-world ramifications of navigating without the ability to fear….The book will be a worthwhile addition to the collections of graduate students and professionals. Highly recommended. Graduate students; researchers and faculty; professionals.--Choice Reviews, 1/2/2017ƒƒLiving Without an Amygdala is a very readable compendium of historical, scientific, and clinical information about the amygdaloid complex, the brain's yellow/red, caution/stop signs. The title…compels even an experienced student of neuroscience to start reading, motivated by the possibility that he or she will discover something about his or her own problems with memory, decision making, and emotional intelligence….Living Without an Amygdala documents the wide-ranging emotional states and psychopathological conditions that are affected by the absence of amygdala….The editors and contributors to Living Without an Amygdala make it abundantly clear that amygdala is much more than the yellow/red, caution/danger flags and signposts on the brain's information-processing superhighway and provide the reader with indispensable background for creating novel hypotheses and planning future research about how our brains construct emotional experiences.--PsycCRITIQUES, 1/9/2017"Over the past several decades much has been learned about the role of the amygdala in behavior, mostly from studies of nonhuman animals. This volume makes a useful contribution by bringing together the current state of knowledge about the human amygdala."--Joseph E. LeDoux, PhD, Center for Neural Science and Department of Psychology, New York University
"Living without an Amygdala provides an important corrective to the popular belief that the primary function of the amygdala is to create a state of fear. The elegant research in this volume affirms the adage that ugly facts often destroy beautiful ideas, and provides neuroscientists and psychologists with a richer understanding of the amygdala."--Jerome Kagan, PhD, Department of Psychology (Emeritus), Harvard University
"This book offers a novel window into the function of the amygdala across development by interweaving controlled primate studies of amygdala lesions with detailed histories of humans who have bilateral amygdala damage. The marriage of experimental neuroscience with personal and empathic narratives results in an informative, compelling work. This book will surely become a classic for students, instructors, and researchers who study the amygdala, human fear and anxiety, and the etiology of mental disorders. It should be of much interest in courses on affective and cognitive neuroscience, as well as abnormal psychology, psychiatry, and developmental psychopathology."--Katie McLaughlin, PhD, Department of Psychology, University of Washington
Descriere
Bringing together leading researchers, this book comprehensively covers what is known about the amygdala, with a unique focus on what happens when this key brain region is damaged or missing. Offering a truly comparative approach, the volume presents research on rats, monkeys, and humans.