The bombing of Pan Am flight 103 in 1988 over Lockerbie, Scotland, and the politics that suround this early anti-US terrorist act provide a fascinating case study in international relations. The event severely impacted Libya's relationship with the United States, the United Kingdom and the United Nations. This work examines all facets of the Lockerbie tragedy including the police investigation and indictment of two Libyan citizens, the imposition of international sanctions against Libya, that country's response and the years of tension and conflict that followed, the role of political mediation (most notably Prince Bandar bin Sultan and President Nelson Mandela), the trial in the Netherlands, Muammar Qaddafi and Libya's increasing maturity in dealing with complex international situations, and the flight 103 bombing's significance within the context of the events of September 11, 2001.