Routinely applied procedures are commonly performed among healthy infants. Pain associated with routinely applied procedure, could be harmful because we do not know what painful experiences the infant has already had and whether this pain might contribute to an acumulative pain experience. Although healthy infants undergoing immunisation often do so with minimal pain relief, immunisation pain can be managed using non-pharmacological interventions, such as oral sweet solutions. The application of sweet solutions which is a simple and quick intervention will minimise the stress and discomfort associated with immunisation, and it can help health care providers to consider and develop a planned approach to manage pain, which in turn could improve the well-being of developing infants.