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Looking at Ribozymes: From Atomic to Molecular and Cellular Scales

Autor Fabrice Leclerc, Benoît Masquida
en Limba Engleză Hardback – 30 noi 2019
Looking at Ribozymes: From Atomic to Molecular and Cellular Scalesintroduces ideas on how ribozymes “work” through a comparison of their common features and specificities. It covers how the (macro) molecular organization at different scales make it possible, what function they carry, where they are found, how they evolved, and how have they been used. The book emphasizes common and specific features of natural and artificial ribozymes, from the basics, to more advanced aspects, making it ideal for undergraduates, grad students and researchers. Specific sections cover different areas of research, from the atomic scale (catalysis), to the molecular (folding, dynamics).
In addition, other sections cover macromolecular and cellular scales (dynamics, long-range interactions, self-assembly, cellular processes). The book is not a directory of ribozymes, it instead provides comparative knowledge, including the interdependent relationships between the different scales of description based on different experimental and theoretical approaches.


  • Give key ideas about how ribozymes work
  • Explain the functioning of the (macro) molecular organization at different scales
  • Focus on the common and specific characteristics of natural and artificial ribozymes
  • Compare interrelated relationships between different scales of description
  • Provide a new way of looking at ribozymes that can be a source of inspiration
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Specificații

ISBN-13: 9781785482106
ISBN-10: 1785482106
Pagini: 130
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Public țintă

Undergraduate and PhD students, scientists working in the fields of ribozymes, RNA, catalysis and enzymes
Scientists interested in the fields of RNA and evolution

Cuprins

1. RNA: from non-enzymatic to enzymatic catalysis
2. Catalytic diversity in ribozyme subclasses
3. Folding, structure and dynamics of ribozymes
4. Long-range interactions and macromolecular assemblies
5. Molecular adaptation during evolution
6. Ribozymes in Cellular Processes: from viroids to eukaryotes
7. Natural and artificial ribozymes: evolution and design