He was her BFF until life got in the way. Now he's back, right when she needs him most. But crossing the line of friendship will risk more than just their hearts. All Jane Porter Allen ever wanted was a big family, front porch, and white picket fence. That dream was laid to rest alongside her husband, Casey, when their life was just getting started. Now, as their son, Noah, faces a similar life-threatening diagnosis, she's forced to confront her past as she struggles with how to save her little boy's future. Enter Ryan Engstrom, Jane's college bestie and Casey's childhood best friend. A pediatric neurosurgeon, he's full of regrets and determined to help Noah. He'll need to move mountains to make sure Noah receives the best medical treatment possible-all the while fighting his own personal demons as he faces a heart-wrenching decision. Though still deeply grieving past traumas, Jane and Ryan are just as in tune with each other as ever. When their feelings grow beyond friendship, everything hangs in the balance, including Noah's life. Now, they must confront their pain and make a choice-continue on separate paths and miss out on a second chance at love, or risk everything to find a way to build a future together. Love on the Brain is a poignant emotional journey that explores love, loss, and the healing of wounds that prove most resistant to it.