This book describes techniques of synthesis and self-assembly of macromolecules for developing new materials and improving functionality of existing ones. Because self-assembly emulates how nature creates complex systems, they likely have the best chance at succeeding in real-world biomedical applications. * Employs synthetic chemistry, physical chemistry, and materials science principles and techniques * Emphasizes self-assembly in solutions (particularly, aqueous solutions) and at solid-liquid interfaces * Describes polymer assembly driven by multitude interactions, including solvophobic, electrostatic, and obligatory co-assembly * Illustrates assembly of bio-hybrid macromolecules and applications in biomedical engineering