This book covers state of the art interdisciplinary research on key disruptive and interrelated technologies such as Big Data, Edge computing, IoT and Cloud computing. The authors address the challenges from a distributed system perspective, with clear contributions in theory and applications. Real-world case studies look at the integration of these technologies in healthcare, disaster management, smart grids, and other areas. The book covers vital topics including devices and sensing; cloud and edge Infrastructure; big data processing; application resource management; and privacy and security.