This publication about prostate cancer is part of a continuing public and professional education program. During the last decade the therapeutic spectrum of prostate cancer has changed dramatically. This prostate cancer manual is intended to present the complex nature of this cancer, the standard treatments and new therapeutic alternatives that have recently been approved and bring new possibilities of a cure. This manual is not intended as a substitute for professional healthcare. It is a preliminary guide to educate patients about treatment options and about the disease itself, so they will be better prepared to discuss it with their health care practitioners. Due to the high level of the scientific information content, this manual is also for students of medicine and healthcare professionals in general.