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Marine Medicinal Glycomics

Editat de Vitor Hugo Pomin
en Limba Engleză Hardback – 30 iun 2013
Glycomics is an international project that analyses systematically and comparatively the overall and/or specific structural and biological properties of carbohydrates, also known as sugars or glycans, within a repertoire from a given type of cell, tissue, organism, kingdom, or even from a certain environment, as found under specific conditions. Glycomics is one of the latest omics projects to be launched into biology. This was because carbohydrates had been primarily considered as a mere class of structural or energetic molecules. Besides that, structural and functional studies in glycomics are more challenging than other projects, and analytical limitations in glycobiology have impaired the progress. However, with the development of technology, and mostly through recent scientific achievements, innumerous vital biological functions have been uncovered and attributed to the sugars. Moreover, certain glycans may also exhibit effective medicinal properties which have in turn awakened a great interest by pharmaceutical companies. This book compiles and illustrates some of these recent achievements concerning the principle examples of marine sugars with medical properties, such as chitin, chitosan, sulphated polysaccharides, and glycoconjugates. Their therapeutic actions are very broad since they comprise beneficial effects in many systems such as inflammation, coagulation, thrombosis, cancer growth/metastasis, and vascular biology. Additional information about the enzymatic synthesis, chemically modified derivatives, relevance of composing units, and other biochemical properties of these marine medicinal glycans are also discussed herein.
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Specificații

ISBN-13: 9781626185975
ISBN-10: 1626185972
Pagini: 223
Dimensiuni: 189 x 264 x 17 mm
Greutate: 0.62 kg
Editura: Nova Science Publishers Inc

Cuprins

Preface; Marine Derived Functional Biopolymer Chitosan & its Derivatives for Biomedical Applications; N-Acetylglucosamine: Medical Importance of Chitin & Chitosan; Enzymatic Synthesis of Chitin Oligosaccharides with Longer Chains; Therapeutic Potential of Fucoidans in Ischemic Diseases; Polysaccharides Obtained from Marine Organisms in Obesity Control; Application of Marine Polysaccharides in Nanotechnology; Anticoagulant Properties of Marine Polysaccharides; Structure-Function Relationship of Anticoagulant & Antithrombotic Marine Sulfated Polysaccharides of Well-Defined Chemical Structures; Marine Sulfated Glycans with an Unusual Serpin-Independent Anticoagulant Activity; Biological Activities & Health Benefits of Marine-Derived Glycoconjugates; Index.