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Mass Spectrometry for Lipidomics – Methods and Applications de M Holcapek

Mass Spectrometry for Lipidomics – Methods and Applications

Autor M Holcapek
en Limba Engleză Hardback – 21 mar 2023
This systematic overview of lipidomic analysis by the president and vice president of the Lipidomics Society covers international standards of lipid analysis, available technology, key lipid classes, as well as applications in basic research, medicine, pharma and food industry.
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Specificații

ISBN-13: 9783527350155
ISBN-10: 3527350152
Pagini: 752
Dimensiuni: 179 x 259 x 47 mm
Greutate: 1.76 kg
Editura: Wiley Vch
Locul publicării:Weinheim, Germany

Notă biografică

Michal Holcapek obtained his Ph.D. at the University of Pardubice (Czech Republic), where he is now a full professor of analytical chemistry. His research focus is mass spectrometry and its coupling with liquid chromatography and supercritical fluid chromatography, applied mainly in the lipidomic analysis and cancer biomarker research. He is a coauthor of over 130 papers in peer-reviewed international journals, editor of 'Trends in Analytical Chemistry', and a member of the editorial advisory boards of 'Analytical and Bioanalytical Chemistry' and 'Lipids'. He is one of founding members of the Lipidomics Standards Initiative and the International Lipidomics Society, where he is on the position of vice-president. Kim Ekroos is the founder and CEO of Lipidomics Consulting Ltd. He received his Ph.D. degree in biology from the Technical University in Dresden (Germany). His expertise includes high-throughput technologies for the precise assessment of lipidomes enabled by advanced mass spectrometry, automation, and software tools for the discovery of biological architectures and of diagnostic biomarkers for clinical purpose. He is one of the pioneers in the field of lipidomics, with more than 20 years of experience in the academic, industry and regulatory aspects of lipidomics and lipid biology. He is a co-founder of the Lipidomics Standards Initiative (LSI) and the current president of the International Lipidomics Society.

Cuprins

Introduction to Lipidomics ANALYTICAL METHODOLOGIES IN LIPIDOMICS Preanalytics for Lipidomic Analysis Direct Infusion (Shotgun) Electrospray Mass Spectrometry Liquid Chromatography- and Supercritical Fluid Chromatography-Mass Spectrometry Mass Spectrometry Imaging of Lipids Ion Mobility Spectrometry Structural Characterization of Lipids Using Advanced Mass Spectrometry Approaches Lipidomic Identification Lipidomic Quantitation The Past and Future of Lipidomics Bioinformatics LIPIDOMIC ANALYSIS ACCORDING TO LIPID CATEGORIES AND CLASSES Fatty Acids: Structural and Quantitative Analysis Quantitation of Oxylipins in Biological Samples Mass Spectrometry for Analysis of Glycerolipids Lipidomic Analysis of Glycerophospholipid Molecular Species in Biological Samples Sphingolipids Sterol Lipids Bile Acids LIPIDOMIC APPLICATIONS Lipidomic Profiling in a Large-Scale Cohort Cancer Lipidomics Lipidomics in Clinical Diagnostics Lipidomics in Food Industry and Nutrition Lipidomics in Plant Science Lipidomics in Multi-omics Studies Tracer Lipidomics Aging and Alzheimer?s Disease Lipidomics in Cell Biology Microbial Lipidomics