Me and Jesse-Me and Danny describes the adventures and misadventures of two ten-year-old boys living in a small town in western Iowa. The stories are told by two best friends, and are spiced with fantasy, wild imaginations, mysteries which take the boredom out of growing up in a small town. A strange character enters the pictures, turning camping, swimming, fishing, and ordinary exploration into mysteries to be solved. The two precocious pre-teens face a ghost, kidnapping gypsies, escaped convicts, and a suspected spy with a suitcase full of surprises. Daytime battles for supremacy in the "town ditch" and nighttime explorations of a cemetery add excitement to fishing and ghost hunting. The questions often resurface: "Who is Rufus?"" and "Is he friend or foe?"