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Medical and Social Aspects of Alcohol Abuse

Editat de Boris Tabakoff
en Limba Engleză Paperback – 14 mar 2012
Alcohol use affects, either directly or indirectly, nearly all facets of Western civi­ lization. Eastern cultures are also not exempt from the influence of alcohol, and the present decade has been a time of increased alcohol use in all parts of the world. The problems of alcohol abuse and alcoholism are of concern to a variety of professionals in the biomedical and psychosocial health sciences, and-although the alcohol research literature contains much information on the relationships between alcohol ingestion and physiological, neurochemical, pharmacologic, genetic, environmental, and psychological effects in humans and in subhuman spe­ cies-there is at the present time no advanced textbook that integrates the avail­ able information for use by both students and professionals. The writing of Medical and Social Aspects of Alcohol Abuse constitutes an attempt to create a scholarly reference and resource for students, researchers, prac­ ticing clinicians, and paraprofessionals who wish to understand the complex inter­ play of factors related to acute and chronic alcohol intoxication, the effects of alco­ hol on body functions, and treatment approaches to alcohol abusers and alcoholics.
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Specificații

ISBN-13: 9781468444384
ISBN-10: 1468444387
Pagini: 420
Ilustrații: XVI, 404 p.
Dimensiuni: 152 x 229 x 22 mm
Greutate: 0.56 kg
Ediția:Softcover reprint of the original 1st ed. 1983
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

1 Alcohol Use and Abuse: Historical Perspective and Present Trends.- 1. Alcohol Use in Historical Perspective.- 2. Alcohol Consumption and Alcohol Problems.- 3. Development of the Concept(s) of Alcoholism.- 4. References.- 2 The Genetics of Alcoholism.- 1. Types of Studies Supporting a Genetic Influence in Alcoholism.- 2. Possible Biological Mechanisms for a Genetic Influence in Alcoholism.- 3. A Prospective Search for the Biological Determinants of Alcoholism.- 4. Summary.- 5. References.- 3 The Absorption, Distribution, and Metabolism of Ethanol and Its Effects on Nutrition and Hepatic Function.- 1. Introduction.- 2. Absorption and Distribution.- 3. Pharmacokinetics and Alcohol Elimination Rates.- 4. Processes and Organs Responsible for Ethanol Elimination.- 5. Significant Pathways of Ethanol Metabolism.- 6. Enzymes That Oxidize Ethanol to Acetaldehyde.- 7. Enzymes That Oxidize Acetaldehyde to Acetate.- 8. Control of Ethanol and Acetaldehyde Metabolism in Liver.- 9. Effect of Chronic Ethanol Ingestion on Alcohol Elimination Rate.- 10. Chronic Ethanol Ingestion and Nutrition.- 11. Ethanol Oxidation and Hepatic Metabolism.- 12. References.- 4 Effects of Ethanol upon Organ Systems Other than the Central Nervous System.- 1. Introduction.- 2. Ethanol and the Gastrointestinal Tract.- 3. Muscle Systems.- 4. The Hematologic System.- 5. Kidney Disease and Alcoholism.- 6. Pulmonary Disease and Alcoholism.- 7. The Endocrine System and Alcoholism.- 8. Effects of Ethanol on the Hypothalamic-Pituitary-Adrenal Axis.- 9. Effects of Alcohol on the Hypothalamic-Pituitary-Thyroidal Axis.- 10. The Effects of Alcohol on Growth Hormone and Prolactin.- 11. Effects of Alcohol on Vasopressin and Oxytocin.- 12. Biological Markers of Alcoholism.- 13. References.- 5 Ethanol and the Central Nervous System.- 1. Ethanol and Behavior.- 2. Ethanol and Membrane Structure and Function.- 3. Ethanol and Electrical Cellular Activity.- 4. Ethanol and Synaptic Transmission.- 5. Ethanol and Metabolism.- 6. Consequences of Long-term Ethanol Consumption.- 7. Summary.- 8. References.- 6 Neurologic Diseases Associated with Chronic Alcohol Abuse.- 1. Introduction.- 2. Physical Dependence.- 3. Chronic Diseases of the Central Nervous System.- 4. Peripheral Polyneuropathy.- 5. Nutritional Deficiencies.- 6. Conclusions.- 7. References.- 7 Biology of Tolerance and Dependence.- 1. Introduction to Tolerance and Dependence.- 2. Factors Contributing to Tolerance and Dependence.- 3. Classifications and Definitions of Tolerance.- 4. Biochemical Determinants of Ethanol Tolerance.- 5. Characteristics of Physical Dependence on Ethanol.- 6. Etiological Factors Contributing to the Development of Physical Dependence.- 7. Neurochemical Systems Determining Physical Dependence.- 8. Pharmacologic Management of the Acute Alcohol Withdrawal Syndrome.- 9. References.- 8 Alcohol Consumption and Prenatal Development.- 1. Fetal Alcohol Syndrome/Fetal Alcohol Effects.- 2. Alcohol as a Teratogen in Animals, 1973–1979.- 3. Critical Discussion and General Conclusions.- 4. References.- 9 Interaction of Ethanol with Other Drugs.- 1. Introduction.- 2. Centrally Acting Compounds.- 3. References.- 10 Psychological Correlates and Explantions of Alcohol Use and Abuse.- 1. Psychodynamic Models.- 2. The Disease Model.- 3. Behavioral and Social-Learning Approach.- 4. Future Directions.- 5. References.- 11 Alcoholism Treatment Approaches: Patient Variables, Treatment Variables.- 1. Critical View of Treatment Outcome Evaluation.- 2. Treatment Variables.- 3. Patient Variables.- 4. Implications.- 5. References.- 12Prevention of Alcohol Abuse.- 1. Approaches to Prevention.- 2. Alcohol Education.- 3. Mass Media.- 4. Alcohol Control Legislation.- 5. Conclusions.- 6. References.