Pharmacognostical and Pharmacognostical Screening of the Medicinal Plant Plumeria Alba Linn. (Apocynaceae) in Cancer Therapy, is used in the treatment of ulcers, herpes, scabies and seeds possess haemostatic. The bark is bruised as plaster over hard tumours. Only a very limited research has been carried out on the plant, under the present study assumes singular significance and it is supposed to contribute a great deal to the existing literature. It highlights the macroscopic and microscopic characters of leaf, petiole, physic chemical evaluation and preliminary photochemical studies of the plant. This research concluded that this plant possess significant anticancer activity after applying in vivo and invitro models.