Mesothelioma from Bench Side to Clinic de Alfonso Baldi

Mesothelioma from Bench Side to Clinic

Alfonso Baldi

This multiauthored book describes the maglinant tumour, mesothelioma, and the latest advances in the field. Its purpose is to offer a comprehensive and up-to-date overview of epidemiology, molecular biology, pathology, animal model, diagnosis and therapy of human mesothelioma. This disease has become an international problem due to environmental ambient pollution, and lack of effective therapies. Notwithstanding the rise in interest in this disease at the scientific, clinical and medicolegal level, there are very few textbooks addressing mesothelioma, and even less books completely dedicated to this maglinant tumour.

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Cuprins

Introduction; Preface; Foreword; Embryology, Histology and Anatomy of Mesothelium; Signalling Involved in Epithelial-mesenchymal Transitions: From embryogenesis to Cellular Pathogenesis; Epidemiology of Mesothelioma: The Role of Asbestos; Non-Asbestos Causes of Mesothelioma; Pathogenesis of Mesothelioma; Molecular Pathways involved in the Patheogensis of Mesothelioma; Cell-cycle Molecules in Mesothelioma; Oxidative Stress and Activation of Survival Pathways as a Basis for Mesothelioma Pathogenesis: New Perspectives for Experimental Therapy; Functional Genomic applications in Understanding Molecular Basis of the Mesothelioma Progression: Use of Transcriptomics and Proteomics Technologies; Transcriptional Profiling of Malignant Pleural Mesothelioma Using Microarrays; Cyclooxygenase Enzymes: Structure, Function and Involvement in Mesothelioma; The SV40 hypothesis: evidence against a role for SV40 in the pathogenesis of mesothelioma; Pathology of Maglinant Mesothelioma; The Immunohistochemical Picture of Mesothelioma; The role of Cytology in the Diagnosis of Serosal Neoplasms; Non Pleural Mesotheliomas; Reactive Mesothelial Proliferations and Benign Mesotheliomas: A Practical Approach; Natural History of Human Pleural Mesothelioma; Clinical Oncology of Mesothelioma; Staging of Malignant Pleural Mesothelima; Possible Roles for Soluble Mesothelin-related Proteins as Tumour Markers for Malignant Mesothelioma; The Radiology of Mesothelioma; Instrumental Diagnosis of Mesothelioma: The Thoracoscopy; Non-surgical Treatment of Malignant Pleural Mesothelioma: Radiotherapy and Chemotherapy.; Surgical Management of Malignant Pleural Mesothelioma; Surgical Therapy of Mesothelioma: The Experience of the Regina Elena Cancer Inst.; Cytoreductive Surgery Combined with Perioperative Intraperitoneal Chemotherapy for Diffuse Malignant Peritoneal Mesothelioma: Prognostic Features of Long- term Survivors; Reconstructive Procedures After Surgical Excision Of Mesothelioma; A Survey on European Ongoing or Planned Clinical Trials in Malignant Pleural Mesothelioma; Clinical trials in Mesothelioma: Australia; US Trials in Mesothelioma; Canine Mesothelioma: An Epidemiological and Preclinical model; Medico-legal and Economic Aspects of Mesothelioma; Index.