Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers
Autor Jacopo Troisi, Martina Lombardien Limba Engleză Paperback – noi 2025
The first section of the book presents the practical basics of metabolomics analysis, from sample collection to data analysis, presenting the entire workflow of a metabolomics experiment. This is crucial for proper framing of the second section of the book, which describes in depth the results obtained and goals set by metabolomics in major fields of medicine. The book concludes the discussion with an explanation of the international regulatory framework a researcher must navigate in order to conduct a metabolomics study in the medical field.
- Describes the basic principles of systems biology and the role of metabolomics
- Explains the basic principles of metabolomics experimentation in terms of both experimental design and laboratory analysis
- Details the main uses of metabolomics profiling for the diagnosis and prognosis of major human diseases and how it can be applied in the study of various diseases
- Analyzes and outlines the European and US regulatory framework regarding the use of artificial intelligence technologies and in particular machine learning in public health
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Specificații
ISBN-13: 9780443236778
ISBN-10: 0443236771
Pagini: 460
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0443236771
Pagini: 460
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Cuprins
1. Metabolomics in system biology
2. The metabolomics workflow: fundamentals of chemical analysis
3. Data analysis approaches in untargeted metabolomics
4. Targeted metabolomics in investigating human diseases
5. Biomarker discovery: pros and cons
6. Metabolomic profiling in screening and prognosis
7. Personalized Medicine approaches: interpreting the metabolome
8. Prenatal medicine: metabolomics contribution and future targets
9. Metabolomics in the study of autoimmune diseases: evidence and perspectives
10. From neurodevelopmental to neurodegenerative disorders: insights from the metabolome lens
11. Cancer Metabolomics: is cancer a metabolic disease?
12. Future perspectives
13. International normative aspects
2. The metabolomics workflow: fundamentals of chemical analysis
3. Data analysis approaches in untargeted metabolomics
4. Targeted metabolomics in investigating human diseases
5. Biomarker discovery: pros and cons
6. Metabolomic profiling in screening and prognosis
7. Personalized Medicine approaches: interpreting the metabolome
8. Prenatal medicine: metabolomics contribution and future targets
9. Metabolomics in the study of autoimmune diseases: evidence and perspectives
10. From neurodevelopmental to neurodegenerative disorders: insights from the metabolome lens
11. Cancer Metabolomics: is cancer a metabolic disease?
12. Future perspectives
13. International normative aspects