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Metchnikoff and the Origins of Immunology: From Metaphor to Theory de Alfred I. Tauber

Metchnikoff and the Origins of Immunology: From Metaphor to Theory: Monographs on the History and Philosophy of Biology

Autor Alfred I. Tauber, Leon Chernyak
en Limba Engleză Hardback – 30 oct 1991
This fascinating intellectual history is the first critical study of the work of Elie Metchnikoff, the founding father of modern immunology. Metchnikoff authored and championed the theory that phagocytic cells actively defend the host body against pathogens and diseased cells.In this scientific biography, Tauber and Chernyak explore Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction. They discuss the profound impact of Darwin's theory of evolution on his progress, and the influence of 19th century debates on vitalism, teleology, and mechanism. As a case study of scientific discovery, this work offers lucid insight into the process of creative science and its dependence on cultural and philosophic sources.
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Specificații

ISBN-13: 9780195064476
ISBN-10: 019506447X
Pagini: 280
Ilustrații: 1
Dimensiuni: 237 x 155 x 24 mm
Greutate: 0.58 kg
Editura: Oxford University Press
Colecția OUP USA
Seria Monographs on the History and Philosophy of Biology

Locul publicării:New York, United States

Cuprins

Foreword; Preface; Introduction; Metchnikoff's early embryology; Metchnikoff's embryological studies after 1872; The problem of evolution in Metchnikoff's works; Metchnikoff's emerging concept of inflammation; The phagocytosis theory and its reception; The phagocyte eclipsed; Epilogue: From metaphor to theory; Notes and references; Appendix A: Morphologists vs. Darwinians, the modern debate; Appendix B: Current views of phagocyte function.

Recenzii

Tauber and Chernyak have produced a scholarly and detailed study of the origins of the deep and long controversy between the cellular and humoral basis of immunity.
In their important, original, and, indeed, definitive contribution to the history of science and philosphy, the authors ... meticulously trace the evolution of these radical and generally misunderstood ideas ... careful and thorough scholarship ... this well-crafted book also provides tactile and visual pleasure.
The richness of this book is due to a fruitful interaction between the American immunologist Tauber and the Russian philosopher Leon Chernyak... An absorbing book for historians of science and medicine as well as professional immunologists.
This book has the merit of exposing the originality of Metchnikoff's claims by setting them against examples from the orthodox literature of the period.Tauber and Chernyak have written an important book. . . , this book offers a rich reward.
Tauber and Chernyak have written an important book ... this book offers a rich reward.
It is a thorough study of the life of Metchnikoff, supplemented with extensive citations from his works and other biographical literature, including the original Russian source ... the book Metchnikoff and the Origins of Immunology provides an excellent example of the fruitful approach to the history of science ... especially useful for everybody interested in immunology and related fields.
the book Metchnikoff and the Origins of Immunology provides an excellent example of the fruitful approach to the history of science ... It can serve both as a comprehensive biography of the great scientist and an interesting case study of one of the brightest discoveries in biology. It also contributes greatly to our understanding of the history of biology and the deep historical roots of modern immunology; this feature distinguishes the book from standard biographical literature and makes it especially useful for everybody interested in immunology and related fields.
a very important work ... a fascinating glimpse into the world of geology and immunology in Russia since the end of the last century ... a welcome addition to the growing English language sources on this neglected field of scientific endeavour