Monografiya posvyashchena resheniyu krupnoy nauchnoy problemy, imeyushchey vazhnoe khozyaystvennoe znachenie - formirovaniyu metodologii sinteza informatsionno-izmeritel'nykh sistem fiziko-khimicheskogo sostava i svoystv veshchestv, obespechivayushchey sozdanie tekhnicheskikh ustroystv, udovletvoryayushchikh trebovaniyam k naznacheniyu, usloviyam primeneniya i tekhniko-ekonomicheskim kharakteristikam. Pri formirovanii metodologii sistematizirovany strukturnye skhemy sistem; proanalizirovany pokazateli pogreshnostey, nadezhnosti, bystrodeystviya, materialoemkosti, energopotrebleniya, stoimosti; klassifitsirovany zadachi sinteza i razrabotany algoritmy ikh resheniya. Prakticheskoy realizatsiey metodologii yavlyayutsya sistemy analiza pochv, sozdannye v ramkakh Prodovol'stvennoy programmy; pervaya v SSSR avtomatizirovannaya sistema raskhoda prirodnogo gaza; odni iz pervykh v SSSR i Rossii khemilyuminestsentnye ustroystva oksidov azota, ammiaka, ozona, arsina, fosfina, monogermana; rentgenofluorestsentnye khimiko-analiticheskie kompleksy tyazhelykh metallov, udostoennye premii Pravitel'stva Rossiyskoy Federatsii; sistema kontrolya kisloroda, a takzhe ustanovka izmereniya azota i geliya v raketnom toplive, razrabotannye dlya kosmodromov Baykonur i Plesetsk.