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Microbial Metabolism and Disease

Autor Elena L. Paley
en Limba Engleză Paperback – 18 mar 2021
Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer’s disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body.


  • Explores microbial metabolic pathways in the human body and implications for disease
  • Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways
  • Considers a variety of diseases and disorders, such as Alzheimer’s disease, metabolic syndromes, Crohn’s disease and Covid-19
  • Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health
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Specificații

ISBN-13: 9780323884457
ISBN-10: 0323884458
Pagini: 306
Ilustrații: 80 illustrations (30 in full color)
Dimensiuni: 191 x 235 x 22 mm
Editura: ELSEVIER SCIENCE

Cuprins

1. Naturally occurring affectors of initial step of protein biosynthesis2. Physicochemical, biochemical and cell biology properties and byproducts of tryptamine and other “trace” amines3. Tryptophan metabolites and biogenic amines in physical exercises4. Tryptamine in inflammation and regulation of gene transcription5. Genes encoding mammalian, plant and microbial aromatic amino acid decarboxylase6. Decarboxylases producing tryptamine and other biogenic amines in human microbiome7. Microbial shikimate pathway in diseases8. Biogenic amines in fasting, feeding and stress conditions9. Metabolites of shikimate and tryptophan pathways in Corona virus disease (COVID-19)10. Virulence factors11. Relation of human gut Alzheimer’s disease associated sequence (ADAS) with shikimate pathway metabolites12. Benefits of using fecal microbiota transplantation as treatment have been controversial13. Shikimate pathway enzymes in human microbiome14. Tryptophan operon in human microbiome and inhibitors of tryptophan operon enzymes15. Antibodies to tryptamines16. Cell death in Alzheimer's disease brain and tryptamine-treated cells