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Microbiota Brain Axis: A Neuroscience Primer

Autor Jane Foster, Gerard Clarke
en Limba Engleză Paperback – 22 feb 2024
Microbiota Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct effective microbiota-brain research, understand the appropriate methodologies, and collect and analyze microbiota data. The book begins with an introduction to the importance of the microbiota-brain communication in development and how microbiota impact neurodevelopmental disorders, mental health and neurodegeneration. In addition, the book discusses advances in microbiota analysis tools and techniques for neuroscience related research.

  • Reviews the many approaches to manipulating the microbiota in animal studies - including the use of germ-free animals, antibiotics and diet - and covers the strengths and limitations of each
  • Outlines available microbiota research tools, such as 16S sequencing and shot-gun metagenomics
  • Provides a comprehensive guide to analyzing microbiota-related data and the many choices for bioinformatics
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Specificații

ISBN-13: 9780128148006
ISBN-10: 0128148004
Pagini: 278
Dimensiuni: 152 x 229 x 16 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE

Public țintă

Advanced students, basic researchers, and clinical researchers in behavioral neuroscience, neuroimmunology, biological psychiatry, developmental neuroscience, and related fields; researchers in physiology, nutrition, immunology, and gastroenterology

Cuprins

1. The gut-brain axis
2. What is a healthy microbiome?
3. Gene-environment factors influence microbiota composition, diversity, and function
4. Microbiota to brain communication
5. Microbiota influence behaviour – work in animal models
6. Microbiota influence brain systems – work in animal models
7. Microbiota in neurodevelopmental disorders
8. Microbiota in psychiatry
9. Microbiota-brain interactions in aging and neurodegeneration
10. Pharmacological treatments and the microbiome - Antibiotics and nonantibiotic drugs
11. Microbial-related treatments
12. Microbiota-related biomarkers for precision medicine and drug discovery