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Mitochondria and Cancer: From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse

Editat de Babak Behnam, Maria Vliora, Sumel Ashique, Farzad Taghizadeh-Hesary
en Limba Engleză Paperback – aug 2025
Mitochondria and Cancer: From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse is a crucial reference aimed at enhancing the understanding of cancer pathogenesis, therapy resistance, and disease relapse linked to mitochondria. This book merges fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It covers a wide range of topics, highlighting the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhancing strategies, and targeted therapies. Unique topics such as applying magnetic fields to target mitochondria are also discussed, offering novel insights. The manuscript is written at a moderate to advanced technical level, making it suitable for researchers, academics, and professionals in cancer biology, molecular biology, and related fields. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. The book's distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research. This makes Mitochondria and Cancer: From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse an invaluable resource for anyone seeking to deepen their understanding of the relationship between mitochondria and cancer.

  • Combines fundamental scientific knowledge with clinical relevance, covering a wide array of topics from mitochondrial metabolism to innovative therapeutic strategies
  • Features unique topics such as applying magnetic fields to target mitochondria, offering cutting-edge approaches to cancer treatment and management
  • Includes contributions from experts across different countries and institutions, providing a well-rounded, global view of current research in mitochondrial involvement in cancer
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Specificații

ISBN-13: 9780443405358
ISBN-10: 0443405352
Pagini: 220
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE

Cuprins

1. Mitochondria: Origin, Structure, and Function
2. Mitochondrial Metabolism and Trafficking in Cancer
3. Mitochondrial Genome and Cancer
4. Mitochondrial-nuclear Crosstalk and Its Role in Cancer
5. Mitochondria and Tumor Microenvironment
6. Mitochondria and Cancer Stem Cells
7. Mitochondria, Exosome, Cancer
8. Mitochondria, Microbiota, Cancer
9. MiRNAs and Their Impacts on Cancer Cell’s Mitochondria
10. Mitochondria and Cancer Prevention
11. Mitochondria and Cancer Diagnosis
12. Mitochondrial Metabolism as a Prognostic Biomarker (Mitochondria and Cancer Progression)
13. Mitochondria, Tumor Microenvironment, and Radioresistance
14. Mitochondria and Resistance to Chemotherapy
15. Mitochondria and Resistance to Targeted Therapies
16. Mitochondria and Resistance to Immunotherapy
17. Mitochondria Enhancing Strategies in Cancer
18. Advances in Targeted Anti-mitochondrial Therapies
19. Applying Magnetic Fields to Target Mitochondria