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Modelling and Analysis of Nonnecrotic Tumors: An Integrative Approach

Autor Anca-Voichita Matioc
en Limba Engleză Paperback – 31 oct 2012
Modelling and simulation of tumor growth is one of the challenging frontiers of applied mathematics. We study in this work a mathematical model for the growth of nonnecrotic tumors in different regimes of vascularisation. The tumor is treated as an incompressible fluid, tissue elasticity is neglected, and the mathematical model is a moving boundary problem. In the radially symmetric case we establish the existence of a unique radially symmetric stationary solution and show, that if the initial tumor is radially symmetric, there exists a unique radially symmetric solution of the problem, which exists for all times. The asymptotic behaviour of this solution it is also discussed. If we consider star-shaped initial tumor domains, we can re-express the mathematical model as an abstract evolution equation. Using general results for parabolic equations we prove the well-posedness of the model. The stability properties of the radially symmetric equilibrium are studied using the principle of linearised stability . Finally, we show, via a bifurcation argument, that there exist also other stationary solutions of the problem, which are no longer radially symmetric.
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Specificații

ISBN-13: 9783838113241
ISBN-10: 3838113241
Pagini: 140
Dimensiuni: 152 x 229 x 8 mm
Greutate: 0.21 kg
Editura: Sudwestdeutscher Verlag Fur Hochschulschrifte