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Modelling Recurrent Event Data with Application toCancer Research

Autor Juan R Gonzalez
en Limba Engleză Paperback – 10 noi 2013
The aim of this book is to show how to analyze survival data with the presence of recurrent events applied to cancer settings. Throughout, the emphasis is on presenting analysis of real data. Many of the models discussed are those widely used in this area. In addition, a new model specially designed for analyzing cancer data is presented. Modern techniques such as penalized likelihood approach, nonparametric smoothig and bootstrapping are developed and used when appropriate. The author, jointly with other colleagues, has written three R packages, freely available at CRAN (http:://www.r-project.org) designed to analyze recurrent event data: gcmrec, survrec and frailtypack. These packages also contain the real data sets analyzed in this book. Each chapter of this book ends with an illustration of how to use these packages to fit models. These analyses should help biostatisticians, clinicians or medical doctors to analyze their own data arising form studies where the main aim is to describe those clinical factors that are associated with the time until a new event occurs taking into account the repeated nature of the data.
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Specificații

ISBN-13: 9783836474641
ISBN-10: 3836474646
Pagini: 184
Dimensiuni: 151 x 227 x 18 mm
Greutate: 0.28 kg
Editura: VDM Verlag Dr. Müller e.K.

Notă biografică

Juan R González is an Assistant Research Biostatistician at the Center for Research in Environmental Epidemiology (CREAL) and an Associate Professor at the Biostatistic Unit, Public Health, University of Barcelona (UB). His current research focuses on developing new statistical methods and R programs to analyze genomic data