Simulated counterflow chromatigraphic separations exhibit a complex dynamical behaviour. In this thesis, two new concepts for the control of these processes, and a new concept for the state reconstruction are presented. From a detailed process model, which encounters the continuous and the discrete dynamics separately, strongly simplified models are derived for the synthesis of the system. Thereby, control and observation algorithms of low complexity are obtained. The practical relevance of the results is shown by numerical simulations.