Molar-Incisor Hypomineralisation has been suggested to be firstly seen as early as 17th century following an examination of archaeological sub-adult samples of a London cemetery.In 2001 for first time the term Molar-Incisor Hypomineralisation (MIH) was introduced following a meeting during the 5th Congress of the European Academy of Paediatric Dentistry. The condition is attributed to disrupted ameloblastic function during the transitional and maturational stages of amelogenesis.The exact nature of the systemic insult is poorly defined.The porous exposed subsurface enamel and the dentine may promote bacterial penetration into the dentine resulting in chronic inflammation of the pulp, and difficulties in obtaining adequate local analgesia. Thus the child may be more anxious about treatment, needing considerable behavioural management. Hence, ideal treatment options may not be possible and alternative treatment plans may be needed.This book contains in detail information regarding the evolution of MIH term to the evaluation of different researches conducted worldwide. It includes the pioneer and the landmark study of MIH conducted in India and the guidelines for the MIH studies.