Molecular and Cellular Therapies for Motor Neuron Diseases
Editat de Nicholas M Boulis, Deirdre O’Connor, Anthony Donsanteen Limba Engleză Hardback – 15 ian 2017
Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.
- Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases
- Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance
- Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy
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Specificații
ISBN-13: 9780128022573
ISBN-10: 0128022574
Pagini: 336
Dimensiuni: 152 x 229 x 23 mm
Greutate: 0.62 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0128022574
Pagini: 336
Dimensiuni: 152 x 229 x 23 mm
Greutate: 0.62 kg
Editura: ELSEVIER SCIENCE
Public țintă
Advanced graduate students, researchers, and clinicians in the fields of neuroscience, neurology, and gene and cell therapyCuprins
1. Molecular and Extracellular Cues in Motor Neuron Specification and Differentiation 2. Natural History of Amyotrophic Lateral Sclerosis 3. Genetics of Amyotrophic Lateral Sclerosis 4. Molecular Mechanisms of Amyotrophic Lateral Sclerosis 5. An Introduction to the Natural History, Genetic Mapping, and Clinical Spectrum of Spinal Muscular Atrophy 6. Genetics of Spinal Muscular Atrophy 7. Introduction to Gene and Stem-Cell Therapy 8. Gene Therapy for Amyotrophic Lateral Sclerosis: Therapeutic Transgenes 9. Stem Cell Therapy for Amyotrophic Lateral Sclerosis 10. Gene Therapy for Spinal Muscular Atrophy 11. Cellular Therapy for Spinal Muscular Atrophy: Pearls and Pitfalls 12. Clinical Trials to Date