Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews our understanding of the molecular mechanisms involved in conception, pregnancy, labor, and birth, and how molecular techniques are being applied to reproductive and perinatal health. The contributors discuss the gene expression profiles and epigenetic characteristics of sperm, the ovary, the endometrium, and the placenta, as well as the molecules involved in feto-maternal communication, including various endocrine, vascular, and immune factors. They also consider how we can harness this knowledge to improve fertility, conception rates, and embryo implantation success, leading to healthy, full-term pregnancies.
The authors also review innovative technologies to diagnose genetic disorders at the fetal and neonatal stages and the social and ethical dilemmas these pose. The volume is therefore an indispensable reference for all scientists and physicians interested in deepening our understanding of human reproductive biology and improving our chances of having healthy children.