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Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds: NATO Science Series A:, cartea 202

Editat de Emel Arinç, John B. Schenkman, Ernest Hodgson
en Limba Engleză Paperback – 12 dec 2012

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Specificații

ISBN-13: 9781468472868
ISBN-10: 1468472860
Pagini: 512
Ilustrații: 508 p. 55 illus.
Dimensiuni: 178 x 254 x 27 mm
Greutate: 0.88 kg
Ediția:Softcover reprint of the original 1st ed. 1991
Editura: Springer Us
Colecția Springer
Seria NATO Science Series A:

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Cytochrome P450-Dependent Monooxygenase: An Overview.- The Flavin-Containing Monooxygenase (EC 1.14.13.8).- Multiple Forms of Rabbit Cytochrome P450: Comparison of Chemical, Physical, Immunological and Biocatalytic Properties.- Primary Structures and Regulation of Cytochrome P450 Isozymes 2 (IIB) and 5 (IVB) and the Flavin-Containing Monooxygenase in Rabbit Liver and Lung.- Insect Cytochrome P450.- I. Membrane Topology of Cytochromes P450: Elements and Measurement by Spectroscopic Techniques.- II. Membrane Topology of Cytochromes P450: Oligomers and Cooperativity.- NADPH-Dependent Cytochrome P450 Reductase A. Y. H. Lu.- Essential Features of NADH Dependent Cytochrome b5 Reductase and Cytochrome b5 of Liver and Lung Microsomes.- Electron Transfer from Cytochrome b5 to Cytochrome P450.- Functional Aspects of Protein-Protein Interactions of Cytochrome P450, Cytochrome b5 and Cytochrome P450 Reductase.- Posttranslational Modification by Phosphorylation: Control of Cytochrome P450 and Associated Enzymes.- Physiological and Pathophysiological Alterations in Rat Hepatic Cytochrome P450.- Ontogenesis of Liver Cytochromes P450.- Mechanism of Steroid Hormome Action A. Berkenstam.- Xenobiotic Regulation of Cytochrome P450 Gene Expression.- Prostanoid Metabolism and Biologically Active Product Formation.- Role of Cytochrome P450 in the Anabolism and Catabolism of Endobiotics.- Interactions of Estrogenic Pesticides with Cytochrome P450.- Effects of Inhibitors on the P450-Dependent Metabolism of Endogenous Compounds in Fungi, Protozoa, Plants and Vertebrates.- Mechanism of Metabolic Activation of Nitroimidozoles.- Benzene Metabolism R. Snyder.- Mechanisms of Benzene Toxicity.- Hematotoxicity, Leukemogenecity and Carcinogenecity of Chronic Exposure to Benzene.- Epoxide Hydrolase Isoenzymes and Their Individual Contribution to the Control of Toxic Metabolites.- Role of the Weil-Known Basic and Recently Discovered Acidic Glutathione S-Transferases in the Control of Genotoxic Metabolites.- Characterisation and Regulation of UDP-Glucuronosyltransferases.- Molecular Cloning, Expression and Genetic Deficiencies of UDP-Glucuronosyltransferases.- Contributors.