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Monoclonal Antibodies

Editat de Marie A. Simmons
en Limba Engleză Hardback – 2 feb 2006
This new and important international source of information beings together leading-edge research dedicated to monoclonal antibodies. Monoclonal antibodies (MAbs) are: antibodies of exceptional purity and specificity; components of the immune system; able to recognise and bind to a specific antigen. Monoclonal antibodies are currently utilised in many diagnostic procedures, including: measuring protein and drug levels in serum; typing tissue and blood; identifying infectious agents; identifying clusters of differentiation for the classification and follow-up therapy of leukaemias and lymphomas; identifying tumour antigens and auto-antibodies; identifying the specific cells involved in the immune response; identifying and quantifying hormones. For example, monoclonal antibodies (MABs or MOABs) work on cancer cells in the same way natural antibodies work, by identifying and binding to the target cells. They then alert other cells in the immune system to the presence of the cancer cells. MABs are specific for a particular antigen-one designed for a B-cell lymphoma will not work on cells for ovarian cancer cells for example.
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Specificații

ISBN-13: 9781594542473
ISBN-10: 1594542473
Pagini: 171
Ilustrații: tables & charts
Dimensiuni: 188 x 261 x 18 mm
Greutate: 0.63 kg
Ediția:New.
Editura: Nova Science Publishers Inc

Cuprins

Preface; Binding Properties of Antibodies to Bacterial Capsular Polysialic Acids: Implications to Vaccination Against Meningitis; A Monoclonal Antibody Against a-Enolase Plasminogen Receptor with Inhibitory Properties: A Useful Tool to Study Pericellular Plasminogen Activation; Quantitative Analysis of Antibody-Antigen Interactions Using Immobilised Ligands: Kinetic Exclusion Assays Are More Accurate than Surface Plasmon Resonance; ABCIXIMAB; Trastuzumab: The Experience of the Hellenic Cooperative Oncology Group (HeCOG); Dimenthyl Sulfoxide-induced Stimulation on Monoclonal Antibody Production is Regulated by P38 Mitogen-activated Protein Kinase in Hybridoma Cells; Effect of Anti-Mouse Interleukin-6 Receptor Antibody in Autoimmune Mouse Models; Index.