Moving Toward Nonanimal Approaches in Medical Research and Testing
Editat de Gail Van Norman, Catharine Krebsen Limba Engleză Paperback – mai 2025
- Presents an overview of historical, ethical, and regulatory issues regarding animal and nonanimal research
- Delivers up-to-date information on the latest in nonanimal experimental advances and methods
- Provides practical guidance about overcoming funding, publication, and other hurdles for nonanimal research
- Discusses practical approaches to advancing nonanimal research and subjugating publication bias to animal research
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Specificații
ISBN-13: 9780443265143
ISBN-10: 0443265143
Pagini: 300
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0443265143
Pagini: 300
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Cuprins
PART 1: THE NEED TO MOVE AWAY FROM ANIMAL-BASED RESEARCH AND TESTING: HISTORICAL, ETHICAL, LEGISLATIVE, AND SCIENTIFIC CONTEXT
1. Philosophical and religious foundations of animal-based research
2. Legislative history of animal-based research
3. Lack of reliability, validity, translatability of animal-based research
4. Animal, financial, and human costs of animal research
5. The individual and systemic preference for animal-based methods: Animal methods bias in publishing and funding
PART 2: ADVANCES IN NONANIMAL METHODS FOR RESEARCH AND TESTING
6. Organoids
7. Microphysiological systems
8. In Silico modeling, supercomputing
9. Bioprinting
10. Other potential topics
11. Human subjects as alternatives to animal subjects in medical research
PART 3: ACHIEVING A PRACTICAL SHIFT TOWARD NONANIMAL-BASED RESEARCH AND TESTING
12. Mitigation efforts in the United States: Overcoming the inertia against nonanimal research
13. International Mitigation efforts: Overcoming the inertia against nonanimal research
14. The industry perspective
15. Getting grants for nonanimal studies
16. Publishing nonanimal studies
17. Building trust in nonanimal methods through standardization, validation, benchmarking, reporting
1. Philosophical and religious foundations of animal-based research
2. Legislative history of animal-based research
3. Lack of reliability, validity, translatability of animal-based research
4. Animal, financial, and human costs of animal research
5. The individual and systemic preference for animal-based methods: Animal methods bias in publishing and funding
PART 2: ADVANCES IN NONANIMAL METHODS FOR RESEARCH AND TESTING
6. Organoids
7. Microphysiological systems
8. In Silico modeling, supercomputing
9. Bioprinting
10. Other potential topics
11. Human subjects as alternatives to animal subjects in medical research
PART 3: ACHIEVING A PRACTICAL SHIFT TOWARD NONANIMAL-BASED RESEARCH AND TESTING
12. Mitigation efforts in the United States: Overcoming the inertia against nonanimal research
13. International Mitigation efforts: Overcoming the inertia against nonanimal research
14. The industry perspective
15. Getting grants for nonanimal studies
16. Publishing nonanimal studies
17. Building trust in nonanimal methods through standardization, validation, benchmarking, reporting