Multifunctional Nanoparticles for Cancer Therapeutic Applications: Design and Challenges describes the use of multifunctional nanoparticles for cancer treatment, highlighting their toxicological evaluation and opportunities for prospective clinical therapeutic development. Besides significant research and clinical success, cancer nanomedicines currently face challenges towards clinical translation and this book aims to shed a light on complex issues. It discusses topics such as synthetic strategies and functionalization of nanoparticles; routes of administration; biological barriers and how to overcome them; nanoparticles for cancer treatment available in the market; active targeting approach; non-viral gene-based therapy with multifunctional nanoparticles; and the use of nanoparticles in immunotherapy. In addition, it discusses image guided cancer therapy; stem cell targeted therapy; and toxicity. It is a valuable resource for cancer researchers, oncologists, clinicians, and members of biomedical field who need to understand the potential of multifunctional nanoparticles in cancer drug delivery, diagnosis, and treatment.

• Presents an interdisciplinary approach on the application of nanoparticles in cancer therapy by bringing together experts from academia, clinical setting, and industry
• Addresses the main clinical challenges for the therapeutic use of nanoparticles for cancer treatment, including toxicity evaluation for specific cancer types
• Focuses on intervening the biological barriers with combinational cancer therapies with the use of multifunctional nanoparticles