Mutagenesis in Sub-Mammalian Systems: Status and Significance
Editat de G.E. Pageten Limba Engleză Paperback – 16 feb 2012
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Specificații
ISBN-13: 9789401166416
ISBN-10: 9401166412
Pagini: 248
Ilustrații: 231 p.
Dimensiuni: 148 x 210 x 13 mm
Greutate: 0.3 kg
Ediția:Softcover reprint of the original 1st ed. 1979
Editura: SPRINGER NETHERLANDS
Colecția Springer
Locul publicării:Dordrecht, Netherlands
ISBN-10: 9401166412
Pagini: 248
Ilustrații: 231 p.
Dimensiuni: 148 x 210 x 13 mm
Greutate: 0.3 kg
Ediția:Softcover reprint of the original 1st ed. 1979
Editura: SPRINGER NETHERLANDS
Colecția Springer
Locul publicării:Dordrecht, Netherlands
Public țintă
ResearchCuprins
Section One General Background to Mutagenesis Studies.- 1 Mutagenesis — the significance of DNA damage for man.- 2 The role of Drosophila in mutagen testing.- Discussion.- Section Two Bacterial Tests for Mutagenesis.- 3 A strategy to minimize human exposure to environmental chemicals causing cancer and genetic birth defects.- 4 Practical experience in testing unknowns in vitro.- 5 Induced mutation in micro-organisms: validity for estimating risk to man.- Discussion.- Section Three Other Mutagenesis Test Systems.- 6 Sub-mammalian tests other than the Ames test for mutagenesis.- 7 Cytogenetic aspects of mutagenicity testing.- 8 Cell transformation assays.- 9 Implications of carcinogenicity.- Discussion.- Section Four General Implications of Mutagenesis.- 10 Extrapolation of mutagenic test results to man.- 11 Tests for mutagenesis from a regulatory point of view.- Discussion.- Round Table Discussion.- Concluding Remarks.