Tuberculosis is regarded as one of the most widespread diseases in all parts of the world and posed a risk to public health, according to the world health organization (WHO) statistics for the year 2005, there are 1.7 billion people are infected with TB (about one third the world population).At the global level about the victims of this disease (3) million people a year are expected to die about (30) million people in this contract as a result of tuberculosis, almost four times the number of deaths due to disease HIV and AIDS in the same period of time. Bovine TB is considered the most important types of tuberculosis transmitted from animals to humans, where livestock are the main reservoir for this disease.The bovine tuberculosis around the proportion of 5-20% of the incidence of tuberculosis in general in humans and this means that there are about (6 million) people expected their death as a result of bovine tuberculosis, the current ten years, and there are most cases of tuberculosis in developing countries, including the Arab Republic of Egypt and the spread of M. bovis in the human being is clearly inherent in the spread in cattle and this one of the best ways to eliminate it