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Myelin: Biology and Chemistry

Editat de Russell E. Martenson
en Limba Engleză Hardback – 20 feb 1992
Myelin: Biology and Chemistry provides in-depth reviews and discussions regarding recent findings in the biology and chemistry of myelin. Topics are interdisciplinary and carry readers from the cellular level to that of the gene. Research in demyelinating diseases (naturally occurring and experimentally produced) is described and emphasizes autoimmune and virally induced mechanisms. Advances in molecular biology, such as those that provide details of the structures of the major myelin proteins, demonstrate the control of their synthesis, and explore the mutations within their genes that disrupt the process of myelination, are discussed in depth. Myelin: Biology and Chemistry will be an important addition to the libraries of molecular biologists, biochemists, cell biologists, physical chemists, immunologists, virologists, and pathologists involved in the study of myelin.
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Specificații

ISBN-13: 9780849388491
ISBN-10: 084938849X
Pagini: 976
Ilustrații: 37 tables and 36 halftones
Dimensiuni: 178 x 254 mm
Greutate: 1.91 kg
Ediția:New.
Editura: CRC Press
Colecția Routledge

Public țintă

Postgraduate

Cuprins

PREFACE (Russell E. Martenson). MYELIN STRUCTURE AND COMPONENTS. Organization, Phylogenetic Variations, and Dynamic Transitions of Myelin (Daniel A. Kirschner and Allen E. Blaurock). CELL BIOLOGY OF MYELINATION. The Oligodendrocyte Lineage during Myelination and Remyelination (Monique Dubois-Dalcq and Regina Armstrong). The Cell of Schwann: An Update (Robert M. Gould, Kristjan R. Jessen, Rhona Mirsky, and Gihan Tennekoon). Axonal Contact as a Determinant of Oligodendrocyte and Schwann Cell Function (Timothy J. Neuberger and George H. De Vries). MYELIN LIPIDS. Interactions of Lipids with Proteins of Myelin and its Associated Cytoskeleton (Peter J. Brophy). Synthesis and Turnover of Myelin Phospholipids and Cholesterol (James W. DeWille and Lloyd A. Horrocks). STRUCTURE AND MOLECULAR BIOLOGY OF THE MAJOR MYELIN PROTEINS. Structure and Acylation of Proteolipid Protein (Marjorie B. Lees and Oscar A. Bizzozero). The Myelin Proteolipid Protein Gene and its Expression (Wendy B. Macklin). Structure and Molecular Interactions of Myelin Basic Protein and its Antigenic Peptides (George L. Mendz). Molecular Genetics of Myelin Basic Protein (John Kamholz and Lawrence Wrabetz). Myelin Basic Protein Isoforms: Structural and Evolutionary Implications of Alternative Exon Splicing (Russell E. Martenson). Myelin-Associated Glycoprotein: Structure-Function Relationships and Involvement in Neurological Diseases (Richard H. Quarles, David R. Colman, James L. Salzer, and Bruce D. Trapp). 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase: Molecular Characterization and Possible Functional Significance (Yasuzo Tsukada and Tadashi Kurihara). Structure and Molecular Biology of P0 Protein (Keiichi Uyemura, Kunio Kitamura, and Masayuki Miura). Myelin P2, A Neuritogenic Member of the Family of Cytoplasmic Lipid-Binding Proteins (Russell E. Martenson and Keiichi Uyemura). MYELIN-ASSOCIATED ENZYMES, RECEPTORS, AND MITOGENS. Enzymes and Receptors of Myelin (Robert W. Ledeen). Calcium-Activated Neutral

Descriere

Biology and Chemistry will be an important addition to the libraries of molecular biologists, biochemists, cell biologists, physical chemists, immunologists, virologists, and pathologists involved in the study of myelin.