Myeloproliferative Neoplasms: Critical Concepts and Management: Hematologic Malignancies
Editat de Tiziano Barbui, Ayalew Tefferien Limba Engleză Paperback – 23 aug 2016
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Specificații
ISBN-13: 9783662520277
ISBN-10: 3662520273
Pagini: 240
Ilustrații: VIII, 240 p.
Dimensiuni: 178 x 254 mm
Greutate: 0.44 kg
Ediția:Softcover reprint of the original 1st ed. 2012
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Hematologic Malignancies
Locul publicării:Berlin, Heidelberg, Germany
ISBN-10: 3662520273
Pagini: 240
Ilustrații: VIII, 240 p.
Dimensiuni: 178 x 254 mm
Greutate: 0.44 kg
Ediția:Softcover reprint of the original 1st ed. 2012
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Hematologic Malignancies
Locul publicării:Berlin, Heidelberg, Germany
Cuprins
Biology.- Gerneral Issues in the Management of MPNs.- Specific Issues of Treatment in PV and ET.- Treatment of PMF.- Research Issues and Perspectives.
Textul de pe ultima copertă
Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. A number of important questions regarding the diagnosis, prognosis, and treatment of these diseases have arisen following the discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative MPNs.
This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.
This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.
Caracteristici
Comprehensively covers laboratory and clinical advances in polycythemia vera, essential thrombocythemia, and primary myelofibrosis Places special emphasis on the practical issues that challenge physicians in their daily practice Includes recommendations for the optimization and standardization of treatment Written by leading experts in the field Includes supplementary material: sn.pub/extras