NanoCellBiology of Secretion: Imaging Its Cellular and Molecular Underpinnings: SpringerBriefs in Biological Imaging
Autor Bhanu P. Jenaen Limba Engleză Paperback – 19 ian 2012
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Specificații
ISBN-13: 9781461424376
ISBN-10: 1461424372
Pagini: 73
Ilustrații: XII, 70 p. 38 illus., 33 illus. in color.
Dimensiuni: 155 x 235 x 13 mm
Greutate: 0.14 kg
Ediția:2012
Editura: Springer
Colecția Springer
Seria SpringerBriefs in Biological Imaging
Locul publicării:New York, NY, United States
ISBN-10: 1461424372
Pagini: 73
Ilustrații: XII, 70 p. 38 illus., 33 illus. in color.
Dimensiuni: 155 x 235 x 13 mm
Greutate: 0.14 kg
Ediția:2012
Editura: Springer
Colecția Springer
Seria SpringerBriefs in Biological Imaging
Locul publicării:New York, NY, United States
Public țintă
Professional/practitionerCuprins
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists.
Table of contetns:
Introduction.- Materials & Methods.- Porosome Discovery.- Calcium & SNARE-Induced Membrane Fusion.- SNAREs need to reside in opposing membrane.- Membrane curvature dictates SNARE size.- Disassembly of membrane-associated SNARE complex.- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly.- SNAREs br
ing opposing bilayers closer for calcium bridging.- Membrane lipids influence SNARE complex assembly-disassembly.- Vesicle swelling and content expulsion during cell secretion.- Secretory vesicle swelling is required for intravesicular content expulsion.- Molecular mechanism of secretory vesicle swelling.- Presence of beta receptors at the secretory vesicle membrane.- Conclusion and future studies.
Table of contetns:
Introduction.- Materials & Methods.- Porosome Discovery.- Calcium & SNARE-Induced Membrane Fusion.- SNAREs need to reside in opposing membrane.- Membrane curvature dictates SNARE size.- Disassembly of membrane-associated SNARE complex.- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly.- SNAREs br
ing opposing bilayers closer for calcium bridging.- Membrane lipids influence SNARE complex assembly-disassembly.- Vesicle swelling and content expulsion during cell secretion.- Secretory vesicle swelling is required for intravesicular content expulsion.- Molecular mechanism of secretory vesicle swelling.- Presence of beta receptors at the secretory vesicle membrane.- Conclusion and future studies.
Recenzii
“This is a reference discussing the molecular mechanisms of the following problems: Exocytocis, secretion of hormones in pancreatic and excitable cells. … This reference is of use to physiologists, biochemists, cell biologists, and membrane experts.” (Joseph J. Grenier, Amazon.com, September, 2015)