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Nanoparticles and the Immune System: Safety and Effects

Editat de Diana Boraschi, Albert Duschl
en Limba Engleză Paperback – 10 dec 2013
Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage for amplifying immune responses in certain diseases or preventive strategies (e.g. vaccination).


  • Identifies endpoints relevant for assessing hazardous situations, evaluating the impact on immunologically frail populations and how to gauge chronic/cumulative effects
  • Raises the awareness of the importance of knowing the effects of the new nanomaterials on our immune system
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Specificații

ISBN-13: 9780124080850
ISBN-10: 0124080855
Pagini: 138
Ilustrații: Illustrations
Dimensiuni: 152 x 229 x 8 mm
Greutate: 0.2 kg
Editura: ELSEVIER SCIENCE

Public țintă

Toxicologists, material scientists and regulators working in the field of nanosafety.

Cuprins

1. Introduction. How innate and adaptive immunity work
2. Nanoparticles and innate immunity (recognition, reaction/healing vs. chronic inflammation)
3. Nanoparticles and adaptive immunity (T and B cells, antibodies, antigen presentation, autoimmunity)
4. Nanoparticles and allergy/hypersensitivity
5. Nanoparticles and immunological frailty (risk groups)
6. Nanoparticles in medicine
7. Nanoparticles and environmental immunity
8. Summary. Nanoparticle properties vs. immunological mechanisms
9. Conclusions and outlook