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Narcolepsy: Integrating Basic and Clinical Knowledge

Editat de Seithikurippu R. Pandi-Perumal, Ahmed S. BaHammam, Amir Sharafkhaneh
en Limba Engleză Paperback – 17 apr 2025
Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations.

Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It’s the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.

  • Presents broad-based coverage of all aspects of narcolepsy, from the basics of sleep physiology to the latest developments in immunotherapy and gene therapy
  • Emphasizes a patient-centered approach that emphasizes the lived experience of those with narcolepsy and the importance of self-care, coping strategies, and advocacy
  • Features in-depth discussions of comorbidities, such as depression, anxiety, obesity, other comorbid sleep disorders, and their impact on narcolepsy management
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Specificații

ISBN-13: 9780443300042
ISBN-10: 0443300046
Pagini: 500
Dimensiuni: 191 x 235 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE

Cuprins

Part I: PATHOPHYSIOLOGY AND NEUROBIOLOGY
1. Understanding Sleep in Narcolepsy: Sleep Physiology and Neurobiology
2. Pathophysiology of Narcolepsy: Genetics and Immune System
3. The Hypocretin/Orexin, Histamine, and Other Neurotransmitters in Narcolepsy: An Animal Model Perspective
4. The Gut-Brain Axis in Narcolepsy: Emerging Research on Microbiota, Diet, and Sleep

Part II: CLINICAL ASPECTS
5. Types of Narcolepsy and Their Symptoms: Differential Diagnosis and Misdiagnosis
6. Delayed Diagnosis of Narcolepsy: Causes and Implications
7. Diagnostic Tools for Narcolepsy: Sleep Studies, MSLT, and More
8. Narcolepsy in Children and Adolescents: Diagnosis, Management, and Challenges
9. Narcolepsy and Pregnancy: Risks and Strategies for Management
10. Aging with Narcolepsy: Understanding the Unique Challenges for Older Adults
11. Medical Co-morbidities of Narcolepsy
12. More Than Just Narcolepsy: The Importance of Recognizing Concurrent Sleep Disorders
13. Narcolepsy and Circadian Rhythm Disorders: Diagnosis and Management
14. The Hidden Link Between Narcolepsy and Autonomic Dysfunction: A Closer Look
15. Narcolepsy and Metabolic Rate: What Do We Know?
16. Narcolepsy and Driving: Safety Issues and Regulations
17. The Natural History of Narcolepsy: Lessons from Longitudinal Studies
18. Narcolepsy and COVID-19: Implications for Diagnosis, Treatment, and Management
19. Neuroimaging in Narcolepsy: Advances in Understanding Pathophysiology and Diagnosis
20. The Distinctive Characteristics of REM Sleep and Dreams in Narcolepsy

Part III: BEHAVIORAL AND PSYCHOSOCIAL CONSIDERATIONS
21. The Hidden Burden of Narcolepsy: Anxiety and Depression Among Patients
22. Understanding Psychosis and Behavioral Abnormalities in Narcolepsy Patients
23. Narcolepsy and Cognitive Impairment: Causes and Management
24. Coping with Narcolepsy: Lifestyle Changes, Academic Performance Challenges, and Employment Strategies for Success
25. Narcolepsy and Relationships: Navigating Intimacy, Family, and Social Life
26. Narcolepsy and Advocacy: Awareness, Education, and Community Building
27. Voices of Narcolepsy: Patient Perspectives on Living with a Chronic Condition
28. The Complexities of Medico-legal Assessment of Disability in Narcolepsy

Part IV: SPECIFIC MANAGEMENT
29. Current Pharmacological Treatments for Narcolepsy
30. Exploring the Potential of Cognitive Behavioral Therapy as an Adjunct to Medication in Narcolepsy Management
31. Emerging Therapies for Narcolepsy: Immunotherapy, Gene Therapy, and Beyond
32. Exploring the Role of Biomarkers and Epigenetics in Narcolepsy: Implications for Diagnosis and Treatment
33. The Future of Narcolepsy Treatment: What Role Will Artificial Intelligence Play?
34. Narcolepsy and Chronic Pain: Implications and Management
35. Navigating the Economic Costs of Narcolepsy in Managed Care.