Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders
Editat de Michael J. Zigmond, Clayton A. Wiley, Marie-Françoise Chesseleten Limba Engleză Hardback – 19 mai 2022
Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more.
- Links basic, translational and clinical research on disorders of the nervous system
- Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain
- Features new chapters on the effects of aging and isolation on brain health
- Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome
- Features in-text summary points, special feature boxes and research questions
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Specificații
ISBN-10: 0323856543
Pagini: 1134
Dimensiuni: 216 x 276 x 63 mm
Greutate: 3.18 kg
Ediția:2
Editura: ELSEVIER SCIENCE
Public țintă
Advanced students in neuroscience (molecular/cellular, behavioral, systems, cognitive, theoretical/computational, and developmental), neurobiology, neurology, and psychiatry, as well as neuroscience faculty, researchers, and postdoctoral fellows interested in becoming more involved in clinically related researchCuprins
Section I: Introductions 1. A Clinical Neuroscientist’s Overview of Disorders of the Brain 2. Disease around the world
Section II. Developmental Disorders 3. Introduction 4. Developmental Disabilities and Metabolic Disorders 5. Attention Deficit/Hyperactivity Disorder 6. Down Syndrome: A Model for Chromosome Abnormalities 7. Autism Spectrum Disorder 8. Rett Syndrome: From the Involved Gene(s) to Treatment 9. Fragile X-Associated Disorders
Section III. Diseases of The Peripheral Nervous System 10. Introduction 11. Myasthenia Gravis 12. Muscular Dystrophy 13. Peripheral Neuropathies 14. Diabetes and Cognitive Dysfunction, Catrina Sims-Robinson
Section IV. Diseases of the Central Nervous System and Neurodegeneration 15. Introduction 16. Spinal Cord Injury 17. Vascular Diseases of the Nervous System 18. Toxic/Metabolic Diseases of the Nervous System 19. Traumatic Brain Injury 19. Epilepsy 20. Amyotrophic Lateral Sclerosis 21. Parkinson Disease and Other Synucleinopathies 22. Huntington Disease 23. Alzheimer Disease 24. Cerebrovascular Disease – Stroke 25. Prion Diseases
Section V. Infectious and Immune-Mediated Diseases Affecting the Nervous System 26. Introduction 27. Role of Inflammation in Neurodegenerative Diseases 28. Role of Inflammation in Psychiatric Disease 29. Infections and Nervous System Dysfunction 30. Pathobiology of CNS Human Immunodeficiency Virus Infection 31. Emergent Viral infections of the Nervous System 32. Autoimmune and Paraneoplastic Neurological Disorders 33. Fibromyalgia and Chronic Fatigue 34. Multiple Sclerosis
Section VI. Diseases of Higher Function 35. Introduction 36. Disorders of Higher Cortical Function 37. Disorders of Frontal Lobe Function 38. Stress 39. Addictions 40. Sleep Disorders 41. Restless Legs Syndrome 42. Fear-Related Anxiety Disorders and Post-Traumatic Stress Disorder 43. Obsessive–Compulsive Disorder 44. Schizophrenia 45. Bipolar Disorder 46. Pain: From Neurobiology to Disease 47. Migraine 48. Depression and Suicide
Section VII. Diseases of the Nervous System and Society 49. Introduction 50. The Neurological and Psychiatric Consequence of Aging 51. Advances in Ethics for the Neuroscience Agenda 52. Burden of Neurological Disease 53. Stress, Health, and Disparities 54. The impact of isolation on brain health
Descriere
Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function.
Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more.
- Links basic, translational and clinical research on disorders of the nervous system
- Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain
- Features new chapters on the effects of aging and isolation on brain health
- Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome
- Features in-text summary points, special feature boxes and research questions