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Neurodegenerative Diseases de Rommy von Bernhardi

Neurodegenerative Diseases

Autor Rommy von Bernhardi
en Limba Engleză Hardback – 31 mai 2008
This book discusses in detail the different hypothesis and experimental evidence regarding the neurobiological mechanisms involved in neurodegenerative pathology, with an emphasis in Alzheimer's and Parkinson's disease. Since there are many hypotheses for neurodegenerative diseases, there is a real need for a comprehensive view, allowing for integration of the different views for the pathogenic mechanisms of the disease.
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Specificații

ISBN-13: 9781604561678
ISBN-10: 160456167X
Pagini: 219
Ilustrații: tables & charts
Dimensiuni: 186 x 260 x 20 mm
Greutate: 0.64 kg
Ediția:1
Editura: Nova Science Publishers Inc

Cuprins

Introduction; Impact of Intracellular Aß amyloid Peptide in Health and Disease; Soluble Aß Oligomers in Alzheimer's Disease; Inhibitory Effects of Aß-amyloid Aggregates on Synaptic Transmission in Hippocampal Neurons; Role of LIMK1 in Neuronal Degeneration in Alzheimer's Disease; Amyloid-Aß-Peptide Activates the Neuronal C-ABL Tyrosine Kinase/ Signaling the Transduction Pathway; Neuroprotection by Astrocytes Involves Multiple Regulatory Mechanisms; Wnt Signaling and its Importance in Alzheimer's Disease; Glycogen Synthase Kinase 3 (GSK-3) As A Molecular Target for Alzheimer's Disease and Other Tauopathies; Inverse Association Between Cancer and Dementia of the Alzheimer's Type; Wnt Signaling in Spinal cord Connectivity; Protein Nitrotyrosination in Alzheimer's Disease; The Ryanodine Receptors / Calcium Release Channels as Neuronal Redox Sensors; Reactive Oxygen Species Signaling in the Hippocampus; Role of Copper in Alzheimer's Disease and other Neuropathological Disorders; Zn2+-protein Interactions in Normal Brain Physiology and Neuropathology; Iron Toxicity; A Critical Review on its Role in Parkinson's Disease; Index.