Neurotherapeutics in the Era of Translational Medicine
Editat de Richard A. Smith, Brian K. Kaspar, Clive N. Svendsenen Limba Engleză Paperback – 4 dec 2020
- Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders
- Discusses important issues in clinical trials such as design and ethical issues
- Written for neuroscientists, neurologists and pharmacologists
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Specificații
ISBN-13: 9780128164754
ISBN-10: 0128164751
Pagini: 518
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0128164751
Pagini: 518
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Public țintă
neuroscientists, neurologists, neuroscientists, pharmacologists, biotechnology executivesCuprins
1. Development of a molecular therapy for the SOD1 familial variant of ALS
2. Unraveling molecular biology of C9ORF72 repeat expansions in amyotrophic lateral sclerosis-frontotemporal dementia: Implications for therapy
3. Translating molecular therapies for spinal muscular atrophy
4. From uncovering the mechanism of transthyretin aggregation to the drug tafamidis for ameliorating neurodegeneration and cardiomyopathy
5. A novel treatment for Parkinson's disease and ALS: Combined cell
and gene therapies
6. Parkinson's disease: Genetic-driven therapeutic approaches
7. Neural stem cell-mediated brain tumor therapy
8. Advances in migraine therapeutics: The role of calcitonin
gene-related peptide
9. The impact of translational research on the development of therapeutic
agents for multiple sclerosis
10. Advances in treating myasthenia gravis
11. The endocannabinoid system as a target for the treatment
of neurological disorders
12. Identification of biomarkers for diagnosing and monitoring therapy in the treatment of neurologic disorders
13. 3D Alzheimer's disease in a dish: Implications for drug discovery
14. Improving clinical trial efficiency with machine learning models
of disease progression
15. Positron emission tomography imaging agents for evaluating the pathologic features of Alzheimer's disease and drug development
16. Repurposing FDA-approved pharmaceuticals: The development
of Nuedexta
17. Bioethics in the era of translational medicine
18. Government efforts to promote the development of neurotherapeutics for the treatment of neurological diseases
19. Innovative funding models for neurotherapeutics
2. Unraveling molecular biology of C9ORF72 repeat expansions in amyotrophic lateral sclerosis-frontotemporal dementia: Implications for therapy
3. Translating molecular therapies for spinal muscular atrophy
4. From uncovering the mechanism of transthyretin aggregation to the drug tafamidis for ameliorating neurodegeneration and cardiomyopathy
5. A novel treatment for Parkinson's disease and ALS: Combined cell
and gene therapies
6. Parkinson's disease: Genetic-driven therapeutic approaches
7. Neural stem cell-mediated brain tumor therapy
8. Advances in migraine therapeutics: The role of calcitonin
gene-related peptide
9. The impact of translational research on the development of therapeutic
agents for multiple sclerosis
10. Advances in treating myasthenia gravis
11. The endocannabinoid system as a target for the treatment
of neurological disorders
12. Identification of biomarkers for diagnosing and monitoring therapy in the treatment of neurologic disorders
13. 3D Alzheimer's disease in a dish: Implications for drug discovery
14. Improving clinical trial efficiency with machine learning models
of disease progression
15. Positron emission tomography imaging agents for evaluating the pathologic features of Alzheimer's disease and drug development
16. Repurposing FDA-approved pharmaceuticals: The development
of Nuedexta
17. Bioethics in the era of translational medicine
18. Government efforts to promote the development of neurotherapeutics for the treatment of neurological diseases
19. Innovative funding models for neurotherapeutics
Recenzii
"Overall, this is a wonderful book for those interested in or familiar with neuroscience, neurological disease, and biotechnology, who wish to have a historical context while learning about the development of novel neurotherapeutic agents. There are few books that cover such a breadth and depth as this one does. It is quite helpful for its intended audience and does the subject justice. It is a worthy addition to any clinician-scientist's library." --© Doody Review, 2020, Ali A Saherwala, MD, reviewer, expert opinion