Neurotransmitter and Dementia de C. G. Gottfries

Neurotransmitter and Dementia: Journal of Neural Transmission. Supplementa, cartea 30

C. G. Gottfries

S. Nakamura

en Limba Engleză Paperback – 13 iul 1990

Neurotransmitter changes taking place in the brain of patients with dementia disorders, mainly Alzheimer type dementia, are reported. Their role in the pathogenesis of Alzheimer's disease is discussed; and the neurochemical changes are considered as a base for formulating treatment strategies. By studying markers in the cerebrospinal fluid, diagnostic methods may be achieved that will aid in diagnosing subgroups of dememtia.

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Cuprins

Some effects of CNS cholinergic neurons on memory.- Subcellular distribution of acetylcholinesterase in Alzheimer’s disease: abnormal localization and solubilization.- Changes of acetylcholine and choline concentrations in cerebrospinal fluids of normal subjects and patients with dementia of Alzheimer-type.- Disturbance of the 5-hydroxytryptamine metabolism in brains from patients with Alzheimer’s dementia.- CSF ?-endorphin, HVA and 5-HIAA of dementia of the Alzheimer type and Binswanger’s disease in the elderly.- Neuropeptide levels in Alzheimer’s disease and dementia with frontotemporal degeneration.- Changes in signal transduction in Alzheimer’s disease.