Chronic kidney disease is a global major health issue that ultimately leads to end-stage renal disease, a devastating condition requiring costly renal replacement therapy. Given this background, extensive understanding of the pathogenesis of the disease and exploring novel therapeutic targets will help to alleviate disease progression, improve prognosis and reduce its impact on the global economic burden.Currently, primary glomerulonephritis is the leading cause of chronic kidney disease and end-stage renal disease in China and many other countries. Recently, there has been much progress with regard to pathogenesis as well as treatment of primary glomerulonephritis. Clinical data from Chinese studies have significantly contributed to the making of international guidelines and histological classifications of the disease. This book focuses on the cutting-edge knowledge and provides up-to-date information on primary glomerulonephritis. Topics covered are IgA nephropathy, focal segmental glomerulosclerosis, membranous nephropathy, membranoproliferative glomerulonephritis, and crescentic glomerulonephritis.