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New Techniques for Studying Biomembranes: Methods in Signal Transduction Series

Editat de Qiu-Xing Jiang
en Limba Engleză Hardback – 7 apr 2020
New Techniques for Studying Biomembranes describes some of the latest methods used to investigate the dynamic distribution of specific lipids in membranes and their effects on other membrane components. The contributors present important discoveries with respect to lipid analysis and lipid interactions with membrane proteins. Various methods, which have been used to study lipid bilayer structure and lipid organization in membranes, include both in vitro and in vivo membrane systems, and study membrane proteins in various membrane systems.
Key Features:
  • Reviews both in vivo and in vitro analytical technologies and methods for studying membrane structure and function
  • Explores how lipid bilayers and membrane proteins interact
  • Includes contributions from an international team of researchers actively studying membrane structure and function
  • Identifies various diseases whose causes are related to membrane proteins
Related Titles:
Christopher R. Jacobs, Hayden Huang, and Ronald Y. Kwon. Introduction to Cell Mechanics and Mechanobiology (ISBN 978-0-8153-4425-4)
Wendell Lim and Bruce Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1)
Stephen Rothman. Proteins Crossing Membranes: A Scientist’s Memoir (978-0-3670-7449-4)
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Specificații

ISBN-13: 9781138618060
ISBN-10: 1138618063
Pagini: 180
Ilustrații: 44
Dimensiuni: 156 x 234 x 11 mm
Greutate: 0.49 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Methods in Signal Transduction Series


Cuprins

Introduction. Lipid compositions of cell membranes and quantification. Phase behavior and lipid organization in membranes. Atomic Force Microscopy of biomembranes. Secondary Ion Mass spectrometry of membrane lipids. Super-resolution imaging of lipid membranes. Single molecule imaging of lipids and proteins in membranes. Membrane interferometry for studying lipids and proteins. Solid state NMR to study of membrane proteins in membranes. X-ray diffractions from stacked membranes. Neutron diffractions from membrane proteins in membranes. cryoEM of Membrane Proteins in membrane. Single molecular fluorimetry for membrane proteins. FRET measurement of ion channel in membrane. X-ray crystallography of membrane proteins.

Recenzii

"Each chapter begins with an introduction that carefully covers the fundamental
operating principles of each method illuminated by details of its historical
development. This extends to the mathematical functions encountered in the
chapters on scanning angle interference microscopy and the analysis of protein
function in reconstituted membrane systems. Each chapter appears to be well
illustrated and thoroughly referenced. The end result is a concise and
straightforward introduction to the topics selected for each chapter." - Peter J. Kennelly, PhD(Virginia Tech)

Descriere

This book describes methods used to investigate the function and distribution of lipids in membranes. Contributors present discoveries that have to do with lipid analysis and lipid interactions with other components of membranes, such as proteins, receptors, transporters and ion channels.