After her father's death Sabrina Brooks, heiress to the Brooks Chemical Company, is trying to pick up the pieces and put everything together. She soon understands that her new position and assets allow her to benefit the oppressed.
With her newfound resources, Sabrina accesses top-secret government archives of chemical weapons research. With her exceptional chemistry skills, she concocts weaponry for her own use and becomes a vigilante called the Nightcrawler, and launches a guerrilla campaign against the drug gangs of New York.
After NYPD undercover officer Hoyt Wexford becomes friends with her and learns of her secret identity, the two wage war against the ruthless drug cartel called the Octagon and their mysterious leader, Reaper. But even with their resourcefulness and teamwork, can they bring the fiendish arch-criminal to justice?